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Journal Article
Research Support, Non-U.S. Gov't
Review
Energy Constraint as a Novel Mechanism Linking Exercise and Health.
Physiology 2018 November 2
Humans and other species adapt dynamically to changes in daily physical activity, maintaining total energy expenditure within a narrow range. Chronic exercise thus suppresses other physiological activity, including immunity, reproduction, and stress response. This exercise-induced downregulation improves health at moderate levels of physical activity but can be detrimental at extreme workloads.
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