We have located links that may give you full text access.
Nationwide surveillance algorithms for tuberculosis among immigrant workers from highly endemic countries following pre-entry screening in Taiwan.
BMC Public Health 2018 October 4
BACKGROUND: This cross-sectional study was retrospectively performed to assess the trend of tuberculosis (TB) among Taiwan's immigrant workers from highly TB-endemic countries under an intervention of conducting a 4-round follow-up (at 0-3 days and 6, 18, and 30 months post-migration) screening program with initial chest X-ray (CXR) following an overseas, pre-entry normal CXR.
METHODS: The immigrant workers with TB disease enrolled in the Taiwan TB registry database in 2011-2014 were analyzed and linked to an immigrant worker physical exam database to stratify TB case categories of actively screened or not for comparison.
RESULTS: Following pre-entry screening for the admission of CXR-normal immigrant workers from highly endemic countries, the overall TB incidence of 70.6-128.6/100,000 person-years resulted either from a subsequent series of 4-round post-entry active screenings or misalliance algorithms, including passive diagnostics for the illness. Overall, the TB relative risk based on incidence in the immigrant working population was 2.2- to 5.5-fold greater than that among corresponding age Taiwanese, with 14.3% (15.5/100,000 person-years) sputum-smear-positive pulmonary TB (SS+ PTB), 74.2% (80.8/100,000 person-years) sputum-smear-negative (SS-) PTB, and 7.8% (8.5/100,000 person-years) only extra-pulmonary TB (EPTB). Regarding the clinical characteristics, 55.5% TB cases - identified through passive illness diagnostics vs. 44.5% TB cases actively identified through mandatory screenings, were higher in SS+ PTB (adjusted odds Ratio (aOR): 1.5, 95% CI: 1.1-2.0, P = 0.008), higher in SC+ PTB (aOR: 1.4, 95% CI: 1.1-1.7, P = 0.004), higher in concurrent extra-pulmonary TB (aOR: 8.9, CI: 4.5-7.4, P < 0.001), and higher in normal CXR TB (aOR: > 100, CI: 0- > 100, P = 0.908). The TB yields of 3rd- to 4th-round screenings were higher than those of 1st- and 2nd-round screenings and ranged from 52.6-65.3 cases per 100,000 screenings in 2013-2014.
CONCLUSIONS: The multiple post-entry TB screenings with initial CXR for high-risk immigrants could actively reduce TB transmission by finding SS- TB cases at early stages. The TB yields at post-entry 3rd- to 4th-round screenings might imply a persistent reactivation of latent TB. Adding more sensitive, economical screenings and preventive treatments for latent TB infection is a comprehensive approach for accelerating TB elimination.
METHODS: The immigrant workers with TB disease enrolled in the Taiwan TB registry database in 2011-2014 were analyzed and linked to an immigrant worker physical exam database to stratify TB case categories of actively screened or not for comparison.
RESULTS: Following pre-entry screening for the admission of CXR-normal immigrant workers from highly endemic countries, the overall TB incidence of 70.6-128.6/100,000 person-years resulted either from a subsequent series of 4-round post-entry active screenings or misalliance algorithms, including passive diagnostics for the illness. Overall, the TB relative risk based on incidence in the immigrant working population was 2.2- to 5.5-fold greater than that among corresponding age Taiwanese, with 14.3% (15.5/100,000 person-years) sputum-smear-positive pulmonary TB (SS+ PTB), 74.2% (80.8/100,000 person-years) sputum-smear-negative (SS-) PTB, and 7.8% (8.5/100,000 person-years) only extra-pulmonary TB (EPTB). Regarding the clinical characteristics, 55.5% TB cases - identified through passive illness diagnostics vs. 44.5% TB cases actively identified through mandatory screenings, were higher in SS+ PTB (adjusted odds Ratio (aOR): 1.5, 95% CI: 1.1-2.0, P = 0.008), higher in SC+ PTB (aOR: 1.4, 95% CI: 1.1-1.7, P = 0.004), higher in concurrent extra-pulmonary TB (aOR: 8.9, CI: 4.5-7.4, P < 0.001), and higher in normal CXR TB (aOR: > 100, CI: 0- > 100, P = 0.908). The TB yields of 3rd- to 4th-round screenings were higher than those of 1st- and 2nd-round screenings and ranged from 52.6-65.3 cases per 100,000 screenings in 2013-2014.
CONCLUSIONS: The multiple post-entry TB screenings with initial CXR for high-risk immigrants could actively reduce TB transmission by finding SS- TB cases at early stages. The TB yields at post-entry 3rd- to 4th-round screenings might imply a persistent reactivation of latent TB. Adding more sensitive, economical screenings and preventive treatments for latent TB infection is a comprehensive approach for accelerating TB elimination.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app