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JOURNAL ARTICLE
REVIEW

Continuous Renal Replacement Therapy - Who, When, Why and How

Srijan Tandukar, Paul M Palevsky
Chest 2018 September 25
30266628
Continuous renal replacement therapy (CRRT) is commonly employed to provide renal support for critically ill patients with acute kidney injury (AKI); particularly patients who are hemodynamically unstable. A variety of techniques that vary in their mode of solute clearance may be used, including continuous venovenous hemofiltration (CVVH) with predominantly convective solute clearance, continuous venovenous hemodialysis (CVVHD) with predominantly diffusive solute clearance and continuous venovenous hemodiafiltration (CVVHDF), which combines both dialysis and hemofiltration. Herein we compare CRRT with other modalities of renal support and review indications for initiation of renal replacement therapy, and dosing and technical aspects in the management of CRRT.

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