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Single-stage posterior instrumentation and unilateral transpedicular debridement for the treatment of thoracolumbar tuberculosis: three years of follow-up.

World Neurosurgery 2018 September 25
This study aimed to compare the efficacy and safety of single-stage posterior instrumentation and unilateral transpedicular debridement with traditional posterior operation for the treatment of thoracolumbar tuberculosis. 53 patients underwent posterior unilateral transpedicular debridement and pedicle screw fixation (group A), and traditional posterior operation was performed in 44 patients (group B). We compared the outcomes including the correction of kyphosis (Cobb angle), bone fusion, visual analog scale (VAS), Frankel classification, and Short-Form 12-Item Health Survey (SF-12) between two groups. All patients obtained intervertebral bone fusion. The mean time of bone graft fusion was 4.1 months, ranging from 3 to 8 months. Patients in the two groups showed significant improvement in kyphosis correction, SF-12, and nerve function. In addition, single-stage posterior instrumentation and unilateral transpedicular debridement could obtain comparable clinical outcomes for the treatment of thoracolumbar tuberculosis, but had less trauma, higher spinal stability, and better function recovery compared to traditional posterior operation.

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