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Imatinib-induced IgA Pemphigus: Subcorneal Pustular Dermatosis Type.
Indian Dermatology Online Journal 2018 September
Imatinib mesylate, a tyrosine kinase inhibitor, is commonly used in the treatment of chronic myeloid leukemia. IgA pemphigus is a rare bullous dermatosis caused by IgA autoantibodies. Clinical manifestations include localized or generalized itchy blisters and pustules. Drug-induced IgA pemphigus has been rarely reported in the literature till date. Here, we report one such rare case caused by imatinib which responded poorly to oral prednisolone but showed excellent response to tablet dapsone.
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