Add like
Add dislike
Add to saved papers

Microwave-mediated synthesis of zinc oxide nanoparticles: a therapeutic approach against Malassezia species.

A successful protocol was developed to aid in the reduction in dandruff-causing fungi, namely Malassezia globasa and Malassezia furfur . Both the species were isolated from volunteers aged between 20 and 22 suffering from dandruff, cultured ex vivo, and tested against the presence of synthesised zinc oxide nanoparticles (ZnNP). Direct microscopy, scanning electron microscopy (SEM), and biochemical assays specific to Malassezia species were conducted to identify dandruff-causing fungal species. Microwave-mediated synthesis of ZnNP was performed and characterised by UV-vis, X-ray diffraction, and SEM. The nanoparticles were tested against both Malassezia species and proved highly effective in inhibiting these fungi, although M. furfur was more susceptible than M. globosa . An optimum amount of 100 ppm was found to be sufficient to work as an antifungal agent. Synergistic effects of ZnNP with commercial shampoos were tested, and the result showed enhanced antifungal effects. To mimic the natural biofilm formed by these species on human skin, the formation of fungal biofilm was allowed on polystyrene coverslips. ZnNP was effective in eradication biofilm. Since zinc is an essential mineral for all living organism and is considered as biocompatible, the synthesised nanomaterials can be used in the formulation of antidandruff shampoos.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app