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Journal Article
Review
Resolving power in liquid chromatography: A trade-off between efficiency and analysis time.
Journal of Separation Science 2018 September 22
This review describes chromatographic dispersion and different plate-height models frequently used to assess the chromatographic performance of (UHP)LC column technology. Furthermore, different performance indices, including the resolution, the separation impedance, and kinetic plots are discussed allowing to quantify and visualize the resolving power in liquid chromatography. The construction of kinetic plots is explained, and different visualization approaches are highlighted. Finally, key instrument and column-technology developments to advance the kinetic performance limits are discussed and selected state-of-the-art applications are highlighted. This article is protected by copyright. All rights reserved.
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