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JOURNAL ARTICLE
REVIEW
Update on Allergen Immunotherapy.
Allergen immunotherapy has been used for many years in dogs and cats and is the only specific treatment of atopic dermatitis that changes the patho-mechanisms of disease by stimulating allergen tolerance. Subcutaneous administration of allergens is the most commonly used administration route, typically in increasing concentrations (induction period) followed by long-term injection of allergen extract (maintenance therapy). Rush protocols with an abbreviated induction period have been reported and shown to be safe in dogs. More recently, oro-mucosal and intralymphatic administration of allergens has been evaluated in dogs. Approximately two-thirds of patients show good to excellent improvement of clinical signs.
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