The relationship between semen parameters in processed and unprocessed semen with IUI success rate.

OBJECTIVE: The aim of this study was to evaluate the relationship between Semen Parameters and IUI success rate.

MATERIAL AND METHODS: This retrospective study was carried out during a 4 year period (2011-2015) on the medical records of 350 couples admitted at the infertility center of Beast Hospital in Tehran. The participants' data such as age, duration of infertility, semen parameters (including volume, concentration, motility, normal morphology and TMSC) before and after sperm processing as well as the IUI results were extracted from the patients' records. Only the first IUI cycle of the couples was considered. The main outcome criterion for the IUI success was serum positive β-hCG 14 days after IUI. The collected data were analyzed with Mann-Whitney, Chi-Square and Fisher's exact tests.

RESULTS: The overall pregnancy rate for each couple was reported as 23.42% (82/350). There was no significant difference in the mean age of the couple and infertility duration between the groups who achieved pregnancy and those who failed. The two groups did not show any significant difference in pre and post processing of semen parameters (including volume, concentration and TMSC). Sperm motility and normal sperm morphology before and after sperm processing were significantly different between the two groups, respectively ( p=.023 before sperm processing and p= .032 after ) ( p=.032 before sperm processing and p= .007 after).

CONCLUSION: Sperm motility and normal sperm morphology have effect in IUI success.