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ENGLISH ABSTRACT
JOURNAL ARTICLE
[HLA ALLELES IN KAZAKHSTAN AND IN THE GLOBAL GENOFUND].
Georgian Medical News 2018 July
The HLA alleles in the Kazakhstan genofund and in the global genofund were compared. The study was carried out on 2283 Kazakhstan donors, 4 566 antigens by five locuses A, B, C, DRB1, DQB1. Comparison with the global HLA alleles was carried out using https://www.allelefrequencies.net open internet resource created by the Royal Liverpool University Hospital. The database included information on 8 locuses (A, B, C, DRB1, DPA1, DPB1, DQA1, DQB1), collected in different programs for HLA genofund studies (anthropological research, blood and bone marrow donorship, HLA-associated diseases, etc.). The results demonstrated the need in further development of the hemopoietic stem cell (HSC) donor register in the Republic for more effective search for compatible donors.
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