We have located links that may give you full text access.
Dose prescription point in forward intensity-modulated radiotherapy of breast and head/neck cancers.
Radiological Physics and Technology 2018 December
In the forward intensity-modulated radiotherapy (FIMRT) technique of treatment planning, the isocenter cannot fulfill the requirements of the International Commission on Radiation Units and Measurements (ICRU) reference point. This study aimed to propose dose prescription points to be used in breast and head/neck cancer patients treated using the FIMRT technique. Two-hundred patients with head/neck (n = 100) and breast (n = 100) cancers were selected. Treatment plans involved using the FIMRT technique. The suggested reference points (SRPs) for dose prescription were placed at selected locations in the lateral neck site and the tangential site in breast and head/neck cancer patients, respectively. Next, doses at the SRPs (DSRPs ) were compared to the planning treatment volume (PTV)-equivalent uniform dose (EUD) and mean dose in the PTV (Dmean ) extracted from dose-volume histograms. The differences between DSRPs and Dmean for the PTVs were less than 2% in 78 cases and less than 1% in 28 cases. The DSRPs were comparable with the EUD in both types of PTVs; moreover, paired t test analyses indicated that the SRP doses and PTV EUD were statistically similar (p > 0.05). In 116 cases, the discrepancy between DSRP and EUD was less than 2% and less than 1% in 74 cases. The SRPs satisfy the ICRU requirement that the reference point dose should be clinically relevant and representative of the dose throughout the PTV. A consensus on the definition of the reference point is expected to lead to accurate inter-comparison between results from different treatment centers, facilitating the optimization of treatment procedures.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon.British Journal of Haematology 2024 April 9
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app