We have located links that may give you full text access.
Measuring defibrillator surface potentials: The validation of a predictive defibrillation computer model.
Computers in Biology and Medicine 2018 November 2
Implantable cardioverter defibrillators (ICDs) are commonly used to reduce the risk in patients with life-threatening arrhythmias, however, clinicians have little systematic guidance to place the device, especially in cases of unusual anatomy. We have previously developed a computational model that evaluates the efficacy of a delivered shock as a clinical and research aid to guide ICD placement on a patient specific basis. We report here on progress to validate this model with measured ICD surface potential maps from patients undergoing ICD implantation and testing for defibrillation threshold (DFT). We obtained body surface potential maps of the defibrillation pulses by adapting a limited lead selection and potential estimation algorithm to deal with the limited space for recording electrodes. Comparison of the simulated and measured potential maps of the defibrillation shock yielded similar patterns, a typical correlation greater than 0.9, and a relative error less than 15%. Comparison of defibrillation thresholds also showed accurate prediction of the simulations. The high agreement of the potential maps and DFTs suggests that the predictive simulation generates realistic potential values and can accurately predict DFTs in patients. These validation results pave the way for use of this model in optimization studies prior to device implantation.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon.British Journal of Haematology 2024 April 9
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app