We have located links that may give you full text access.
Line Immunoassay: A Rapid Test for Screening TORCH Complex in Antenatal Patients with Bad Obstetric History.
Mymensingh Medical Journal : MMJ 2018 July
TORCH {Toxoplasma gondii, Rubella, Cytomegalovirus (CMV), the Herpes Simplex Virus (HSV)} infection causes pregnancy wastage at any stage of gestation. Serological assays can be an important tool for diagnosis. It includes ELISA which is highly specific & sensitive with certain drawbacks like time consuming and for each genus separate test have to be done. Line-Immunoassay (LIA), a newer, cheaper and reliable technique on contrary is done on single panel strip. The present retrospective study was conducted with the aim to evaluate the efficacy of Line Immunoassay for detection of TORCH IgM antibodies. A total of 630 samples from the pregnant women with Bad Obstetric History (BOH) attending OPD and IPD of Obstetrics and Gynecology Department of Maharishi Markandeshwar Institute of Medical Science & Research (MMIMSR), Mullana, Ambala, Haryana, India from 2011 to 2015 were subjected to Line-Immunoassay and ELISA for detection of IgM antibodies against TORCH agents in Department of Microbiology. The analysis for TORCH complex showed 32.85% positivity by LIA while 36.03% by ELISA. The diagnostic accuracy of LIA when ELISA considered gold standard was also exhibited which showed Sensitivity of 90.75%, Specificity of 99.75% while PPV & NPV were 99.52%, 95.05% respectively. The statistical analysis showed results were statistically insignificant (p value >0.05). Comparison of detection of TORCH IgM antibodies by ELISA & Line-Immunoassay express good sensitivity & specificity requiring significantly less time and low cost by Line-Immunoassay, concludes that Line-Immunoassay may be used as screening test.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
Perioperative echocardiographic strain analysis: what anesthesiologists should know.Canadian Journal of Anaesthesia 2024 April 11
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app