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Determinants of impaired renal and vascular function are associated with higher levels of procoagulant factors in the general population: comment.
Journal of Thrombosis and Haemostasis : JTH 2018 August 24
We read with great interest the article by Dekkers et al. [1] in which the authors reported their attempt to investigate whether estimated glomerular filtration rate (eGFR), urinary albumin-creatinine ratio (UACR), and pulse wave velocity (PWV) were associated with a procoagulant state. In their cross-sectional analysis of the Netherlands Epidemiology of Obesity Study, eGFR, UACR, fibrinogen, and coagulation factors (F)VIII, FIX, and FXI were determined in 6536 participants, and PWV was assessed in 2433 participants. They concluded that in the middle-aged sample of the general population impaired renal and vascular function was associated with higher levels of coagulation factors. We thank the authors for their comprehensive contribution. This article is protected by copyright. All rights reserved.
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