Vulvovestibular Syndrome and Vaginal Microbiome: A Simple Evaluation.

Background: The vulvovestibular syndrome (VVS) is a chronic, inflammatory, multifactorial, chronic inflammation of the female urogenital access.

Methods: The aim of this anecdotal, observational, retrospective, case-control study was to comparatively evaluate the most common bacterial strains ( Lactobacillus spp. , Klebsiella spp. , Gardnerella spp. , and Streptococcus spp. ) and fungi ( Candida spp. , Pennicillum spp ., and Aspergillus spp. ) in vulvodinic women, and in women without gynecological symptoms (control group).

Results: We found that vulvodinic patients had statistically lower Lactobacilli and higher total Fungi concentration.

Conclusions: Our preliminary study is useful to further clarify the etiopathology of vulvodynia and suggest new therapeutic strategies for approaching the VVS.