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Ultrasensitive profiling of multiple biomarkers from single cells by signal amplification mass spectrometry.
Chemical Communications : Chem Comm 2018 August 24
A signal amplification protocol based on mass spectrometry (MS) was developed to profile simultaneously multiple biomarkers from a single cell using various mass label (ML)-modified Au nanoparticles (AuNPs). The strategy with ultrahigh sensitivity and specificity has potential prospects in the deep exploration of molecular and cellular characterization.
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