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Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Systematic Review
Meta-Analysis Reveals the Association Between Male Occupational Exposure to Solvents and Impairment of Semen Parameters.
Journal of Occupational and Environmental Medicine 2018 October
OBJECTIVES: Solvent exposure is among the most common occupational exposures to chemical toxicants; data about the impact of such exposure on semen parameters are contradictory. We conducted the first meta-analysis to evaluate the risk of alteration in semen parameters related to occupational exposure to solvents.
METHODS: From the PubMed database, we selected studies analyzing the semen of subjects occupationally exposed to solvents, compared with unexposed controls. The meta-analysis was performed on the various semen parameters analyzed in both populations.
RESULTS: Seven studies were included in the study. The meta-analysis revealed a significant decrease in ejaculate volume [standardized mean difference (SMD) = -0.35 (-0.63 to -0.07)] and sperm concentration [SMD = -0.36 (-0.64 to -0.08)] in workers exposed to solvents compared with unexposed controls.
CONCLUSION: Our results highlight the importance of preventing reprotoxic risks to male fertility in the workplace.
METHODS: From the PubMed database, we selected studies analyzing the semen of subjects occupationally exposed to solvents, compared with unexposed controls. The meta-analysis was performed on the various semen parameters analyzed in both populations.
RESULTS: Seven studies were included in the study. The meta-analysis revealed a significant decrease in ejaculate volume [standardized mean difference (SMD) = -0.35 (-0.63 to -0.07)] and sperm concentration [SMD = -0.36 (-0.64 to -0.08)] in workers exposed to solvents compared with unexposed controls.
CONCLUSION: Our results highlight the importance of preventing reprotoxic risks to male fertility in the workplace.
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