We have located links that may give you full text access.
The association between Helicobacter pylori seropositivity and low birthweight in a Sudanese maternity hospital.
International Journal of Gynaecology and Obstetrics 2018 November
OBJECTIVE: To investigate the association between Helicobacter pylori seropositivity and low birthweight (LBW).
METHODS: The present case-control study was conducted at a Sudanese maternity hospital from September 1 to December 30, 2015. Patients who delivered single neonates with LBW (>500 g but <2500 g) and the subsequent singleton delivery with birthweight of 2500-4000 g were included. A questionnaire was used to collect medical and obstetric data. The presence of malarial parasites in peripheral, placental, and umbilical cord samples was investigated using blood films. The presence of H. pylori immunoglobulin G (IgG) in maternal and umbilical cord serum samples was determined by enzyme-linked immunosorbent assay.
RESULTS: The study included 87 patients in each of the LBW and control groups. Maternal serum tested positive for H. pylori IgG among 66 (75.9%) and 48 (55.2%) patients in the LBW and control groups (P=0.006); no malarial parasites were observed. Similarly, umbilical cord serum tested positive for H. pylori IgG among 66 (75.9%) and 34 (39.1%) patients in the LBW and control groups (P<0.001). Maternal H. pylori IgG seropositivity (OR 3.2, 95% CI 1.4-7.2; P=0.003) and umbilical cord H. pylori IgG seropositivity (OR 2.4, 95% confidence interval 2.1-10.2; P<0.001) were significantly associated with LBW.
CONCLUSION: Seropositivity for H. pylori IgG was associated with LBW.
METHODS: The present case-control study was conducted at a Sudanese maternity hospital from September 1 to December 30, 2015. Patients who delivered single neonates with LBW (>500 g but <2500 g) and the subsequent singleton delivery with birthweight of 2500-4000 g were included. A questionnaire was used to collect medical and obstetric data. The presence of malarial parasites in peripheral, placental, and umbilical cord samples was investigated using blood films. The presence of H. pylori immunoglobulin G (IgG) in maternal and umbilical cord serum samples was determined by enzyme-linked immunosorbent assay.
RESULTS: The study included 87 patients in each of the LBW and control groups. Maternal serum tested positive for H. pylori IgG among 66 (75.9%) and 48 (55.2%) patients in the LBW and control groups (P=0.006); no malarial parasites were observed. Similarly, umbilical cord serum tested positive for H. pylori IgG among 66 (75.9%) and 34 (39.1%) patients in the LBW and control groups (P<0.001). Maternal H. pylori IgG seropositivity (OR 3.2, 95% CI 1.4-7.2; P=0.003) and umbilical cord H. pylori IgG seropositivity (OR 2.4, 95% confidence interval 2.1-10.2; P<0.001) were significantly associated with LBW.
CONCLUSION: Seropositivity for H. pylori IgG was associated with LBW.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app