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Compressive Myelopathy Secondary to Atlantoaxial Dislocation in a Child with Congenital Hypothyroidism: A Case Report.
Journal of Pediatric Neurosciences 2018 April
Atlantoaxial dislocation (AAD) occurs secondary to joint laxity between C1 and C2 vertebrae, resulting in loss of normal articulation and movement. Etiology of AAD could be genetic, inflammatory, or rarely traumatic. Majority of children with AAD are syndromic (such as Down syndrome) or genetic (such as Ehler-Danlos syndrome or Marfan syndrome). To the best of literature search, there were no reports of AAD among children with congenital hypothyroidism. This case highlights an uncommon association of AAD presenting with features of compressive myelopathy in a child with congenital hypothyroidism. Early detection and neurosurgical intervention could possibly avert this irreversible neurological damage.
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