We have located links that may give you full text access.
Physiological effects of a short-term lifestyle intervention based on the Mediterranean diet: comparison between older and younger healthy, sedentary adults.
Nutrition 2018 November
OBJECTIVE: The aim of this study was to determine whether short-term adherence to the Mediterranean diet (MD) was associated with improved physiological function.
METHODS: This was a single-center, cohort pilot study with 24 healthy, sedentary younger (18-35 y of age) and older (55-75 y of age) adults. Participants were advised to follow the MD for 4 wk. Baseline and post-intervention measurements were taken of weight, height, waist and hip circumference, blood pressure, and heart rate, as well as microvascular physiological assessments using laser Doppler flowmetry (LDF) at rest, as well as transcutaneous oxygen pressure (TcpO2) during a sub-maximal exercise assessment.
RESULTS: We identified statistically-significant improvements in axon-mediated microvascular vasodilation (2.24 ± 0.56 to 3.14 ± 0.84; P = 0.03) and endothelial-mediated nitric oxide synthesis (2.59 ± 0.67 to 3.32 ± 0.87; P = 0.022) in the younger group. Despite the intervention not including an exercise element, the rate of perceived exertion was reduced in both groups (P < 0.001), after following the MD for 1 mo.
CONCLUSIONS: Improvements in physiological function were observed after a short-term dietary intervention based on the MD in a younger population. These were not statistically matched in an older group. Our findings suggest that different durations should be applied when designing dietary interventions in different age groups, with expectations in physiological improvement differing.
METHODS: This was a single-center, cohort pilot study with 24 healthy, sedentary younger (18-35 y of age) and older (55-75 y of age) adults. Participants were advised to follow the MD for 4 wk. Baseline and post-intervention measurements were taken of weight, height, waist and hip circumference, blood pressure, and heart rate, as well as microvascular physiological assessments using laser Doppler flowmetry (LDF) at rest, as well as transcutaneous oxygen pressure (TcpO2) during a sub-maximal exercise assessment.
RESULTS: We identified statistically-significant improvements in axon-mediated microvascular vasodilation (2.24 ± 0.56 to 3.14 ± 0.84; P = 0.03) and endothelial-mediated nitric oxide synthesis (2.59 ± 0.67 to 3.32 ± 0.87; P = 0.022) in the younger group. Despite the intervention not including an exercise element, the rate of perceived exertion was reduced in both groups (P < 0.001), after following the MD for 1 mo.
CONCLUSIONS: Improvements in physiological function were observed after a short-term dietary intervention based on the MD in a younger population. These were not statistically matched in an older group. Our findings suggest that different durations should be applied when designing dietary interventions in different age groups, with expectations in physiological improvement differing.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app