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CASE REPORTS
JOURNAL ARTICLE
Autoimmune hepatitis following influenza virus vaccination: Two case reports.
Medicine (Baltimore) 2018 July
RATIONALE: Although immunization could possibly cause autoimmune hepatitis (AIH), to date, no cases of AIH have been reported secondary to influenza virus vaccination. This paper describes 2 women who developed AIH after receiving influenza virus vaccination.
PATIENT CONCERNS AND DIAGNOSES: Two women presented with elevation of liver enzymes after receiving influenza virus vaccination. Both patients were diagnosed with AIH using the International Autoimmune Hepatitis Group criteria.
INTERVENTION AND OUTCOMES: Both patients were treated with prednisolone. After the initiation of prednisolone, serum aminotransferase levels were observed to return to the reference range in both patients.
LESSONS: Influenza virus vaccination could trigger the development of AIH. Clinicians should be mindful of the fact that AIH can occur after influenza virus vaccination.
PATIENT CONCERNS AND DIAGNOSES: Two women presented with elevation of liver enzymes after receiving influenza virus vaccination. Both patients were diagnosed with AIH using the International Autoimmune Hepatitis Group criteria.
INTERVENTION AND OUTCOMES: Both patients were treated with prednisolone. After the initiation of prednisolone, serum aminotransferase levels were observed to return to the reference range in both patients.
LESSONS: Influenza virus vaccination could trigger the development of AIH. Clinicians should be mindful of the fact that AIH can occur after influenza virus vaccination.
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