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2018 Belgian guidelines for the screening for latent tuberculosis in HIV-infected patients.
Acta Clinica Belgica 2018 July 24
OBJECTIVES: To review the current knowledge on screening for latent tuberculosis infection (LTBI) in HIV-infected adults and provide specific guidelines for Belgium. Focus is given to who to test, which testing method to use, timing of screening and choice of LTBI treatment.
METHODS: Expert review by the members of the Belgian LTBI group, in consultancy with the ARC College.
RESULTS: Target population, timing of screening, testing method, active TB exclusion, treatment of LTBI and guideline implementation are all reviewed.
CONCLUSIONS: The principal changes include a selective approach to screen for LTBI (screening only of the HIV-infected patients at highest risk of active TB) as well as the timing of screening (testing for LTBI performed only after immune-restauration by antiretroviral therapy).
METHODS: Expert review by the members of the Belgian LTBI group, in consultancy with the ARC College.
RESULTS: Target population, timing of screening, testing method, active TB exclusion, treatment of LTBI and guideline implementation are all reviewed.
CONCLUSIONS: The principal changes include a selective approach to screen for LTBI (screening only of the HIV-infected patients at highest risk of active TB) as well as the timing of screening (testing for LTBI performed only after immune-restauration by antiretroviral therapy).
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