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pSTAT3 + Reactive Astrocytes Promote Brain Metastasis.
Trends in Molecular Medicine 2018 September
The tumor microenvironment contains heterogeneous populations of stromal cells with important roles in cancer progression and metastasis. In a recent study published in Nature Medicine, pSTAT3+ reactive astrocytes were found to promote brain metastasis by altering the tumor microenvironment, and represent a promising target for the treatment of brain metastasis.
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