A new crystal form and anti-microbial activity of ( E )-1-[3-(2-hy-droxy-benzyl-idene-amino)-phen-yl]ethanone.

The title Schiff base compound, C15 H13 NO2 , crystallizes in a new crystal form in the space group P 21 21 21 , which is different from the monoclinic P 21 / n space group reported previously [De et al. (2009 ▸). Indian J. Chem. Sect. B , 48 , 595-598]. An intra-molecular O-H⋯N hydrogen bond occurs between the hy-droxy and azomethine moieties. In the crystal, mol-ecules are linked by weak C-H⋯O hydrogen bonds into supra-molecular chains propagating along the b -axis direction with a C (8) graph-set motif. The contribution of these two contacts in Hirshfeld surface area are around 19 and 21%, respectively. The title compound was screened for its anti-bacterial activity against two gram-negative ( Escherichia coli and Salmonella typhimurium ) and one gram-positive ( Staphyloccus aureus) bacteria. The results of this study reveal that this Schiff base shows good activity against only one bacterium, i.e. Salmonella typhimurium .