Neurocryptococcosis in immunocompetent patient with psychosis.

Isabelly Sanally Monteiro Florentino, José Brasileiro Dourado Júnior, Amaury Cantilino

Clinical Schizophrenia & related Psychoses 2018 June 27

BACKGROUND: The involvement of Cryptococcus as an etiological agent in behavioral disorders, such as psychosis, is rare finding.

METHODS: We report the case of 20-year-old man showed apparent functioning behavior premorbid, immunocompetent, with had a first psychotic episode one day after a clinical condition by mild fever, polyarthralgia, headache, fatigue and insomnia and detected cryptococcal antigen latex and India ink positive for Cryptococus neoformans in lumbar puncture. The psychotic episode responded to antifungal and antipsychotic treatment.

CONCLUSIONS: We emphasize the importance of paying attention to subtle systemic and neurological signs and investigating the general medical condition cause in the case of a first psychotic episode.

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