Analgetic Efficacy of Flurbiprofen Axcetil in Rigid Cystoscopy for Men: a Prospective Study.

Objective: To evaluate the analgesic effect of preprocedural flurbiprofen axetil on rigid cystoscopy-associated pain for men.

Methods: Fifty-two men scheduled for cystoscopy were recruited in this study. The effects of oxybuprocaine jelly alone or in combination with preprocedural flurbiprofen axetil, were compared. The pain intensity was assessed using visual analogue scale (VAS) scores during injecting oxybuprocaine jelly into the urethra, during inserting rigid cystoscope into the urethra, during viewing inside the urinary bladder, at the first urination after cystoscopy and at the first urination on the following morning at home.

Results: VAS scores with preprocedural flurbiprofen axetil were significantly lower as compared with the control group at the time periods of inserting rigid cystoscope into the urethra, viewing inside the urinary bladder, the first urination after cystoscopy and at the first urination on the following morning at home. No side effects associated with flurbiprofen axetil were observed.

Conclusion: Preprocedural flurbiprofen axetil can decrease cystoscopy-associated pain.