[Comparative study on deep venous thrombosis onset in hospitalized patients with different underlying diseases].

Objective: To improve the understanding of deep venous thrombosis (DVT), the present study was conducted to investigate the difference of DVT onset in hospitalized patients with different underlying diseases. Methods: This is a single-center retrospective study from Beijing Shijitan Hospital. Clinical data from hospital onset DVT patients from 2007 to 2016 were collected. DVT was confirmed with compression ultrasonography (CUS), color Doppler flow imaging (CDFI), CT venography (CTV), magnetic resonance venography (MRV), lower extremities radionuclide venography(RDV) or conventional venography (CV). The risk factors of DVT in hospital were analyzed with a Chi-square analysis. Results: A total of 5 063 patients (1.65%) with DVT involving 5 024 veins were identified from 305 922 inpatients admitted without DVT during ten years. Among DVT patients, 2 752 were males (54.36%) and 2 311 were females (45.64%) with age of (74.1±15.9) years (range from 1 to 103 years). Patients with DVT were elder and longer inhospital than those without DVT ( P< 0.001). Patients with respiratory diseases had higher incidence of DVT (6.83%, OR= 5.498, 95% CI 5.151-5.868) than those with other system diseases, in which patients with respiratory failure had the highest incidence of DVT (9.53%, 95% CI 6.912-8.018) among all patients. The risks of having DVT were higher in patients with serious internal medicine diseases than those in patients with trauma, or cataclasis/operations, or invasive manipulations. Among all DVT patients, 71.54% of them were with inflammation diseases, 55.56% were with hypertension and 54.93% were with structural heart disease. DVT often occurred in inferior extremities (83.78%, 4 360/5 063) in patients irrespective of underlying diseases. Conclusions: There is an association between underlying diseases of hospitalized patients and the development of DVT. Patients with internal medicine diseases had higher risk to develop DVT than those with trauma or cataclasis/operations or invasive manipulations. To prevent the development of DVT, its screening should be emphasized in patients with serious internal diseases.