We have located links that may give you full text access.
YKL-40 expression in pterygium: a potential role in the pathogenesis.
International Ophthalmology 2018 June 20
PURPOSE: The aim of the study was to evaluate whether YKL-40 (chitinase 3-like 1 protein) plays a role in pterygium pathogenesis.
METHODS: We included 42 primary pterygium patients and 24 control subjects with normal bulbar conjunctiva in the study. The pterygium patients were classified into the atrophic, fleshy, and intermediate groups according to the Tan classification. We then surgically removed the primary nasal pterygium and normal bulbar conjunctiva from the patients and immunohistochemically investigated YKL-40 expression.
RESULTS: YKL-40 expression was statistically significantly higher in the epithelial, endothelial, and stromal cells of the pterygium tissues than in the control tissues (P = 0.009, P = 0.003, P = 0.002, respectively). There was no significant correlation between the pterygium subgroups and YKL-40 expression (P > 0.05).
CONCLUSIONS: We believe YKL-40 may play a significant role in pterygium pathogenesis.
METHODS: We included 42 primary pterygium patients and 24 control subjects with normal bulbar conjunctiva in the study. The pterygium patients were classified into the atrophic, fleshy, and intermediate groups according to the Tan classification. We then surgically removed the primary nasal pterygium and normal bulbar conjunctiva from the patients and immunohistochemically investigated YKL-40 expression.
RESULTS: YKL-40 expression was statistically significantly higher in the epithelial, endothelial, and stromal cells of the pterygium tissues than in the control tissues (P = 0.009, P = 0.003, P = 0.002, respectively). There was no significant correlation between the pterygium subgroups and YKL-40 expression (P > 0.05).
CONCLUSIONS: We believe YKL-40 may play a significant role in pterygium pathogenesis.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app