Association of Androgenetic Alopecia with Metabolic Syndrome: A Case-control Study on 100 Patients in a Tertiary Care Hospital in South India.

Background: Androgenetic alopecia (AGA) is the most common cause of hair loss. Although it is a medically benign condition, it can have a significant psychosocial impact on patients. "Metabolic syndrome" (MetS) is a collection of clinical signs that focus on cardiovascular and diabetes-related parameters. Despite the high burden of AGA and MetS in India, specific data on the participants are relatively sparse.

Aim of the Study: The aim of is to study the association of AGA with MetS and its parameters.

Materials and Methods: A case-control study was undertaken in a tertiary care hospital from December 2015 to November 2016 with 100 cases and controls in the age group of 20-50 years. Diagnosis of MetS was based on the National Cholesterol Education Program Adult Treatment Panel III. Independent t -test was used as a test of significance. Categorical data were assessed using Chi-square test of significance. P <0.05 was considered to be significant.

Results: MetS was seen in 53% of cases and 17% of controls ( P = 0.001). The mean serum triglyceride level ( P = 0.015, P < 0.05), mean systolic blood pressure ( P = 0.003, P < 0.05), high-density lipoprotein levels in males ( P < 0.001), and waist circumference in males ( P = 0.022, P < 0.05) were statistically significant in patients with androgenetic alopecia when compared to healthy controls.

Conclusion: A higher prevalence of MetS was noted in androgenic alopecia. Early screening for MetS is beneficial in patients with androgenic alopecia.