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Refractory Hyperlactatemia After a Septic Shock in a Patient With Carnitine Deficiency: A Case Report.

Philippe Hogan, Roxane Plourde, Maude Fortier, Dave Brindamour, Colin Lagrenade-Verdant, Simon Demers-Marcil, Sébastien Dupuis
Journal of Pharmacy Practice 2018 January 2
A 56-year-old woman with septic shock presented with persistent hyperlactatemia, despite an adequate clinical response to treatment. Carnitine deficiency was suspected, as the patient was malnourished and chronically taking valproic acid. No other plausible cause of hyperlactatemia was found. Carnitine supplementation resulted in rapid normalization of lactatemia.

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