Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea .

Three cyclopentanoids (phlebiopsin A⁻C), one glycosylated p -terphenyl (methyl-terfestatin A), and o -orsellinaldehyde were isolated from the biocontrol fungus Phlebiopsis gigantea , and their structures were elucidated by 1D and 2D NMR spectroscopic analysis, as well as by LC-HRMS. The biological activity of the compounds against the root rot fungus Heterobasidion occidentale , as well as against Fusarium oxysporum and Penicillium canescens , was also investigated, but only o -orsellinaldehyde was found to have any antifungal activity in the concentration range tested.