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CASE REPORTS
JOURNAL ARTICLE
Antiphospholipid Syndrome Complicating Pneumococcal Meningitis.
Indian Pediatrics 2018 May 16
BACKGROUND: Antiphospholipid syndrome is a multisystem auto-immune disorder characterized by arterial or venous thrombosis in children.
CASE CHARACTERISTICS: 11-year-old child with pneumococcal meningitis also had cerebral sinus vein thrombosis and pulmonary artery segmental thrombosis.
OBSERVATION: Pro-thrombotic evaluation showed positive lupus anticoagulant at baseline and after 12 weeks. Investigations for lupus were negative at admission and after one year of follow-up.
MESSAGE: Antiphospholipid syndrome is a possibility even in thrombosis occurring in the setting of meningitis.
CASE CHARACTERISTICS: 11-year-old child with pneumococcal meningitis also had cerebral sinus vein thrombosis and pulmonary artery segmental thrombosis.
OBSERVATION: Pro-thrombotic evaluation showed positive lupus anticoagulant at baseline and after 12 weeks. Investigations for lupus were negative at admission and after one year of follow-up.
MESSAGE: Antiphospholipid syndrome is a possibility even in thrombosis occurring in the setting of meningitis.
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