[Effects of nasal polyps and allergy rhinitis on quantitative evaluation of subjective and objective assessment of chronic rhinosinusitis].

Objective: To investigate the effect of nasal polyps and allergy rhinitis on disease assessment of chronic rhinosinusitis, and to analyze the correlation between subjective and objective scores. Method: A total of 253 patients with chronic rhinosinusitis were enrolled from June 2016 to June 2017, and the clinical data such as sex, age, comorbidity, diagnosis and treatment were summarized. All patients were grouped as with or without nasal polyps, with or without eosinophilia, with or without allergic rhinitis group, and assessed by the visual analogue scale(VAS), Lund-Mackay CT score and Lund-Kennedy score respectively. The difference of the three grades in each group were analyzed by statistic analysis. The correlation between the three grades was analyzed. Result: Two hundred and fifty-three cases of chronic rhinosinusitis were included in the analysis. There were 143 males and 110 females with an average age of 44.44±15.44 years old, mostly in the 41-65 age group, and the difference was statistically significant ( P <0.01). The scores of VAS, Lund-Mackay CT and Lund-Kennedy in the nasal polyp group were significantly higher than those in the non-nasal polyp group ( P <0.05). The nasal endoscopy score of patients with allergic rhinitis was higher than that of non-allergic rhinitis group ( P <0.01). There was no significant difference between VAS score, CT and endoscopic score in EOS group ( P >0.05). There was a positive correlation between VAS score and nasal endoscopy score or CT score ( P <0.01) in patients of non-allergic rhinitis or eosinophilia group, but there was no correlation ( P >0.05) in patients with allergic rhinitis or eosinophilia group. There was no correlation when two or three factors exist at the same time beteen the nasal polyp, allergic rhinitis and EOS group ( P >0.05), whereas show up positive correlation on non-merged group ( P <0.01). Conclusion: Chronic rhinosinusitis complicated with nasal polyps or allergic rhinitis can significantly increase the subjective and objective symptoms of patients. There are differences between subjective symptoms and objective tests in the patients with nasal polyps, allergic rhinitis and EOS factors. Therefore, clinical attention should be paid to the impact of allergic factors on patients, using a variety of subjective and objective evaluation atrategies to evaluate the condition of patients with chronic rhinosinusitis comprehensively, to provide a basis for personalized diagnosis and treatment.