The use of immunohistochemical methods in the study of morphofunctional features of the human paranasal sinuses: literature review.

OBJECTIVE: Introduction:Chronic inflammatory diseases of the mucous membrane of the nose, paranasal sinuses, and pharynx are the most widespread pathology of the upper airways. The thorough study of the features of the organization of local immune protection of the mucous membrane of the paranasal sinuses is crucial for the deep understanding of the causes of the onset and development of this and other pathologies of the paranasal sinuses, the choice of methods of diagnostics and treatment. Consequently, immunohistochemical studies are of great potential and have become preferable for great number of researchers. The aim: The paper was aimed at the analysis of the publications on the use of immunohistochemical methods in the study of the structural and functional features of the paranasal sinuses.

PATIENTS AND METHODS: Materials and methods: The bibliosemantic method has been used during the study. Findings of the current research works on the use of immunohistochemical methods in the study of the paranasal sinuses have been analyzed.

RESULTS: Review:The findings of the analysis shows that the use of immunohistochemical methods in the otorhinolaryngology is becoming more and more popular in the study of both morphofunctional features of the paranasal sinuses and in various experimental studies.

CONCLUSION: Conclusion: The use of immunohistochemical methods in the study of the paranasal sinuses in both clinical otorhinolaryngology and theoretical morphology is relevant to date and is considered reasonable and perspective.