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AP-1 Takes Centre Stage in Enhancer Chromatin Dynamics.

Pedro Madrigal, Kaur Alasoo
Trends in Cell Biology 2018 July
Recent studies involving induced pluripotent stem cell (iPSC) reprogramming in mice and monocyte-to-macrophage differentiation in humans have revealed a role for the transcription factor (TF) activator protein 1 (AP-1) in chromatin accessibility. Enhancer selection may be determined not only by cell type-specific sets of TFs but also by broadly expressed ones like AP-1.

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