JOURNAL ARTICLE
REVIEW
Add like
Add dislike
Add to saved papers

On the potential of ion mobility spectrometry coupled to GC pre-separation - A tutorial.

Analytica Chimica Acta 2018 September 19
In this tutorial, we want to demonstrate the significant potential of ion mobility spectrometry (IMS), an analytical technique for identification and quantification of gas-phase compounds, in particular combined to other useful analytical tools. Coupled to gas-chromatographic pre-separation (GC-IMS), selectivity can be improved significantly, thus enabling the analysis of complex, humid mixtures. In-line pre-concentration can improve sensitivity down to the ppqV range. Furthermore, the use of non-radioactive ionisation sources in the near future could gain acceptance and will avoid legal restrictions. Hence, with suitable and controlled sampling, implementation of appropriate substance and pattern databases and data evaluation software, GC-IMS as rapid, selective and sensitive analytical tool has shown its high potential for many applications in process and quality control, medicine (diagnostics, medication and therapy control), biology, safety and security. In the present tutorial, we want to demonstrate this capacity on behalf of examples from the application fields mentioned above, with particular focus on controlled sampling, pre-concentration and pre-separation as well as on data treatment and interpretation.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app