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N-Heterocyclic Carbene-Catalyzed Annulation of Ylides with Ynals: Direct Access to α-Pyrones.
Chemistry, An Asian Journal 2018 September 5
We herein report an N-Heterocyclic Carbene (NHC)-catalyzed annulation of ylides with ynals that provides an efficient protocol to make 4,6-disubstituted α-pyrones. This method affords a variety of α-pyrones in good to high yields as well as broad substrate scope and good functional group tolerance.
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