Add like
Add dislike
Add to saved papers

Salivary immunoglobulin levels in juvenile autoimmune hepatitis.

AIMS: The aim of the present study was to investigate the presence of immunoglobulins (Ig) in whole saliva from patients affected by autoimmune hepatitis (AIH).

DESIGN: Twelve individuals with AIH and 12 healthy individuals without (CON) autoimmune hepatitis, aged 8-18 years, participated in this study. Non-stimulated whole saliva was collected and centrifuged. Supernatants were separated and lyophilized. Salivary pH was measured and immunoglobulins were analyzed through ELISA technique.

RESULTS: Salivary pH (CON, 7.17 ± 0.45; AIH, 6.92 ± 0.43) did not differ between groups (p = 0.183). Measurable levels of IgG, IgA, IgM and IgE were detected on all patients. IgG levels were higher in AIH individuals (CON, 1.058 ± 0.386; AIH, 1.635 ± 0.373; p = 0.001), whereas IgA (CON, 0.915 ± 0.187; AIH, 0.995 ± 0.235; p = 0.362), IgM (CON, 0.683 ± 0.147, AIH, 0.646 ± 0.161; p = 0.561) and IgE levels (CON, 1.241 ± 0.378; AIH, 1.312 ± 0.412; p = 0.664) did not present differences between groups.

CONCLUSIONS: The results of the present study suggest differences in salivary IgG levels between individuals with and without AIH. Thus, saliva has the potential of becoming an important diagnostic tool for the assessment of AIH.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app