Add like
Add dislike
Add to saved papers

Nongenetic Optical Methods for Measuring and Modulating Neuronal Response.

ACS Nano 2018 May 23
The ability to probe and modulate electrical signals sensitively at cellular length scales is a key challenge in the field of electrophysiology. Electrical signals play integral roles in regulating cellular behavior and in controlling biological function. From cardiac arrhythmias to neurodegenerative disorders, maladaptive phenotypes in electrophysiology can result in serious and potentially deadly medical conditions. Understanding how to monitor and to control these behaviors precisely and noninvasively represents an important step in developing next-generation therapeutic devices. As we develop a deeper understanding of neural network formation, electrophysiology has the potential to offer fundamental insights into the inner working of the brain. In this Perspective, we explore traditional methods for examining neural function, discuss recent genetic advances in electrophysiology, and then focus on the latest innovations in optical sensing and stimulation of action potentials in neurons. We emphasize nongenetic optical methods, as these provide high spatiotemporal resolution and can be achieved with minimal invasiveness.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app