New Insights into Chemistry and Biological Potential of Thiazine Scaffold: A Review.

Heterocyclic compounds bearing nitrogen and sulphur have drawn strong attention due to their useful biological and pharmacological properties. Thiazine is a promising scaffold among these heterocyclic compounds which has been widely utilized in synthesis of compounds that possess interesting biological activities, such as anti-tumour, anti-microbial, antipsychotic, antifungal, antiviral, analgesic and anti-inflammatory. Present review focuses on the chemistry of thiazine and its derivatives as well as potential pharmacological activities reported in scientific literature. The pharmacological profiles of these thiazine derivatives represent a fruitful matrix for further development of superior medicinally active agents.