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English Abstract
Journal Article
[Role of the Nucleolus in Rearrangements of the IGH Locus].
Molekuliarnaia Biologiia 2018 March
The review summarizes the results from a series of studies focusing on the role that the nucleolus plays in maturation of the IGH locus and the choice of its partner genes in leukemia-associated translocations. The role of nuclear compartmentalization and nuclear localization of translocated oncogenes in ectopic activation of their transcription is discussed.
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