We have located links that may give you full text access.
Long-term capsule clarity with a disk-shaped intraocular lens.
Journal of Cataract and Refractive Surgery 2018 April
PURPOSE: To evaluate long-term capsular clarity with a modified disk-shaped 1-piece hydrophilic acrylic monofocal intraocular lens (IOL) (Zephyr) suspended between 2 complete haptic rings connected by a pillar of the haptic material.
SETTING: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
DESIGN: Experimental study.
METHODS: Study and control (1-piece hydrophobic acrylic) IOLs were implanted into the right and left eyes, respectively, of 8 New Zealand rabbits. Eyes were examined at the slitlamp at set intervals for 6 months. At the end of the clinical follow-up, the globes were enucleated and capsular clarity was scored from the posterior view (Miyake-Apple technique). Then, all the eyes were processed for a complete histopathological evaluation.
RESULTS: At 6 months, the slitlamp evaluation showed a posterior capsule opacification score of 0.28 ± 0.26 (SD) in the study group and 4 ± 0 in the control (P < .0001, paired t test). The anterior capsule was generally clear in the study group. This parameter was difficult to analyze in the control group because of synechiae formation and poor pupil dilation.
CONCLUSIONS: The degree of capsular bag clarity observed at 6 months postoperatively in the study eyes in this rabbit model was exceptional. It was likely because of the IOL design, keeping the capsular bag open and expanded, and minimizing contact between the IOL and the anterior capsule.
SETTING: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
DESIGN: Experimental study.
METHODS: Study and control (1-piece hydrophobic acrylic) IOLs were implanted into the right and left eyes, respectively, of 8 New Zealand rabbits. Eyes were examined at the slitlamp at set intervals for 6 months. At the end of the clinical follow-up, the globes were enucleated and capsular clarity was scored from the posterior view (Miyake-Apple technique). Then, all the eyes were processed for a complete histopathological evaluation.
RESULTS: At 6 months, the slitlamp evaluation showed a posterior capsule opacification score of 0.28 ± 0.26 (SD) in the study group and 4 ± 0 in the control (P < .0001, paired t test). The anterior capsule was generally clear in the study group. This parameter was difficult to analyze in the control group because of synechiae formation and poor pupil dilation.
CONCLUSIONS: The degree of capsular bag clarity observed at 6 months postoperatively in the study eyes in this rabbit model was exceptional. It was likely because of the IOL design, keeping the capsular bag open and expanded, and minimizing contact between the IOL and the anterior capsule.
Full text links
Related Resources
Trending Papers
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app