We have located links that may give you full text access.
Tissue intrinsic fluorescence recovering by an empirical approach based on the PSO algorithm and its application in type 2 diabetes screening.
Biomedical Optics Express 2018 April 2
In order to reduce the influence of scattering and absorption on tissue fluorescence spectra, after tissue fluorescence and diffuse reflectance in different tissue optical properties were simulated by the Monte Carlo method, a tissue intrinsic fluorescence recovering algorithm making use of diffuse reflectance spectrum was developed. The empirical parameters in the tissue intrinsic fluorescence recovering algorithm were coded as a particle in the solution domain, the classification performance was defined as the fitness, and then a particle swarm optimization (PSO) algorithm was established for empirical parameters optimization. The skin autofluorescence and diffuse reflectance spectra of 327 subjects were collected in Anhui Provincial Hospital. The skin intrinsic autofluorescence spectra were recovered by using the empirical approach and the integration area of the spectra were calculated as fluorescence intensity. Receiver operating characteristic (ROC) analysis for fluorescence intensity was applied to evaluate the classification performance in type 2 diabetes screening. In addition, a support vector machine (SVM) method was implemented to improve the performance of the classification. The results showed that the sensitivity and specificity were 32% and 76% respectively, and the area under the curve was 0.54 before recovering, while the sensitivity and specificity were 72% and 86% respectively, and the area under the curve was 0.86 after recovering. Furthermore, the sensitivity and specificity increased to 83% and 86% respectively when using linear SVM while 84% and 88%, respectively, when using nonlinear SVM. The results indicate that using the tissue fluorescence spectrum recovery algorithm based on PSO can improve the application of tissue fluorescence spectroscopy effectively.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app