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Evaluation of antimycobacterial activity of Curcuma xanthorrhiza ethanolic extract against Mycobacterium tuberculosis H37Rv in vitro .
Veterinary World 2018 March
Aim: The aim of this study was to evaluate the antimycobacterial activity of the Curcuma xanthorrhiza ethanolic extract in vitro .
Materials and Methods: Ethanolic extract of C. xanthorrhiza was set by maceration method. The broth microdilution and disc diffusion method were used to determine the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC), respectively, of C. xanthorrhiza ethanol extract on strain Mycobacterium tuberculosis H37Rv.
Results: C. xanthorrhiza ethanol extract was found to have the antimycobacterial effects with a MIC value of 1600 μg/ml while MBC value of 3200 μg/ml for M. tuberculosis H37Rv.
Conclusion: From these findings , it can be concluded that C. xanthorrhiz a ethanol extract have an antibacterial activity against Mycobacterium tuberculosi s H37Rv in vitr o and its potency elevated by increasing the C. xanthorrhiz a ethanol extract concentration.
Materials and Methods: Ethanolic extract of C. xanthorrhiza was set by maceration method. The broth microdilution and disc diffusion method were used to determine the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC), respectively, of C. xanthorrhiza ethanol extract on strain Mycobacterium tuberculosis H37Rv.
Results: C. xanthorrhiza ethanol extract was found to have the antimycobacterial effects with a MIC value of 1600 μg/ml while MBC value of 3200 μg/ml for M. tuberculosis H37Rv.
Conclusion: From these findings , it can be concluded that C. xanthorrhiz a ethanol extract have an antibacterial activity against Mycobacterium tuberculosi s H37Rv in vitr o and its potency elevated by increasing the C. xanthorrhiz a ethanol extract concentration.
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