[Two Cases of Neuroendocrine Carcinoma of the Non-Ampullary Duodenum].

Here we report 2 cases of neuroendocrine carcinoma(NEC)of the non-ampullary duodenum which is extremely rare neoplasm. Case 1: A 76-year-old man had a type 2 duodenal carcinoma with a 3 cm-sized lymph node metastasis. Duodenal resection with subpyloric lymph nodes dissection and Roux-en-Y reconstruction were performed. The histopathological diagnosis was NEC of the duodenal bulb after surgery(pT3pN1M0, stage III A, UICC 7th edition). The patient died of chronic heart failure 10 years and 3 months after the surgery. Case 2: A 45-year-old woman had a type 2 duodenal NEC of the second part of the duodenum. A subtotal stomach-preserving pancreatoduodenectomy was performed with lymph node dissection.(pT4pN0M0, stage II B, UICC 7th edition). The patient died of recurrence 7 months after the surgery.