[A Retrospective Study of Preoperative Concurrent Chemoradiotherapy for Locally Advanced Resectable Rectal Cancer].

PURPOSE: To analyze chemoradiotherapy results for locally advanced rectal cancers at a single institution.

METHODS: The study cohort comprised 12 patients with clinically diagnosed T3/4, NX, M0 adenocarcinomas of the rectum who received preoperative chemoradiotherapy.

RESULT: Pathological complete response(pCR)were observed in 2/12(16.7%)patients and pathological downstaging in 5/12(41.7%)patients, with generally mild adverse events.

CONCLUSION: Preoperative che- moradiotherapy for clinical T3/4, NX rectal cancers significantly reduces local recurrences and improves prognoses.