Postoperative Cardiac Surgery Outcomes in a Statin-Native Population.

Background: Statin utilization had been associated with improved survival after cardiac surgery. We aim to study whether perioperative treatment with statin could be associated with increased postoperative complications.

Design: This was a retrospective, descriptive, single-center study.

Settings: We analyzed morbidity after cardiac surgery as well as the outcome related to statin therapy in a tertiary cardiac center.

Patients: A total of 202 consecutive patients were enrolled over 1 year after cardiac surgery.

Intervention: Patients were divided into two groups; Group I - statin users and Group II - nonusers.

Measurements: Measurements were baseline and follow-up laboratory markers for muscular injury including cardiac muscle and hepatic injuries and renal injuries.

Results: The incidence of rhabdomyolysis and elevation of liver enzymes did not differ between both groups. Postoperative atrial fibrillation was significantly lower in the statin group ( P = 0.02). In addition, peak cardiac troponin and creatine kinase-MB did not differ significantly in the statin group. Statin-treated group had significant lower length of mechanical ventilation, and length of stay in the Intensive Care Unit and hospital ( P = 0.036, 0.04, and 0.027, respectively).

Conclusions: Therapy with statin before cardiac surgeries was not associated with high incidence of adverse events.