[NEUROPSYCHIATRY AND COMPUTATIONAL MEDICINE].

INTRODUCTION: The classical model of medicine is based on, first, history taking, followed by physical examination, data analysis by the clinician and their further validation using biological tests. Based on this, the clinician may plan the medical treatment. In neuropsychiatry, this model is even more limited as physical examination is based mostly on a patient-doctor conversation, and biological or imaging tests are directed mostly to extract the structural basis for the clinical manifestations. The rapidly developing computational revolution have not yet significantly influenced this model. Nevertheless, various advancements in machine-learning, algorithms, computation, internet, hardware, sensors, image processing and more intend to change this process profoundly. In this article we will review this process of computational medicine and exemplify how it enables new approaches in the domains of pain and dementia.