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Modification of apparent intracerebral hematoma volume on T2 ∗ -weighted images during normobaric oxygen therapy may contribute to false diagnosis.
Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia 2018 June
It was previously reported that normobaric oxygen therapy (NBO) significantly affected T2∗ -weighted imaging in a mouse model of intracerebral hemorrhage (ICH). However, it is unclear whether a similar phenomenon exists in large volume ICH as seen in human pathology. We investigated the effects of NBO on T2∗ -weighted images in a pig model of ICH. Our data show that NBO makes disappear a peripheral crown of the hematoma, which in turn decreases the apparent volume of ICH by 18%. We hypothesized that this result could be translated to ICH in human, and subsequently could lead to inaccurate diagnostic.
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