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Pilot study: is the fear response the same in anorexia nervosa as in controls?
Eating and Weight Disorders : EWD 2018 March 15
PURPOSE: To determine whether the fear response is the same in AN as in controls.
METHOD: We recorded the EEG in 10 participants with a history of AN and in 10 controls during a fear stimulus. The response of the brain was recorded using EEG LORETA. The recording was analyzed for a marked increase in activity in the amygdala, uncus, insula, and anterior cingulate from 300 to 500 ms following the stimulus.
RESULTS: The order or response of the amygdala, uncus, insula, and anterior cingulate was not significantly different in AN and controls.
CONCLUSION: These results suggest that the brain's response to a fear stimulus is not significantly different in AN and controls.
LEVEL OF EVIDENCE: Level 3, case-control study.
METHOD: We recorded the EEG in 10 participants with a history of AN and in 10 controls during a fear stimulus. The response of the brain was recorded using EEG LORETA. The recording was analyzed for a marked increase in activity in the amygdala, uncus, insula, and anterior cingulate from 300 to 500 ms following the stimulus.
RESULTS: The order or response of the amygdala, uncus, insula, and anterior cingulate was not significantly different in AN and controls.
CONCLUSION: These results suggest that the brain's response to a fear stimulus is not significantly different in AN and controls.
LEVEL OF EVIDENCE: Level 3, case-control study.
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